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| Name | De novo design of discrete, stable 3-10 helix peptide assemblies |
| Video Uploader | Video From Bristol BioDesign Institute |
| Upload Date | This Video Uploaded At 23-06-2022 08:05:08 |
| Video Discription | Credit: Dr Prasun Kumar and Dr Fabio Pirro Uninhibited by the natural precedent for using alpha helices and the beta strands, University of Bristol Research Associate Dr Prasun Kumar designed a protein-like molecule made solely from 3-10 helices. To do this, Prasun combined amino acids - the chemical units of proteins - that are found in natural proteins with others that are not. He made these designer proteins by chemical synthesis and showed that they formed bundles of pure 3-10 helices using X-ray crystallography. This research has been published in an article in Nature: https://www.nature.com/articles/s41586-022-04868-x For more information, see: https://bristolbiodesign.blogs.bristol.ac.uk/2022/06/23/impossible-protein-like-structure-made-by-university-of-bristol-researchers/ Wm0mbLjTuzc |
| Category | Science & Technology |
| Tags | University of Bristol | Prasun Kumar | Dek Woolfson | Woolfson Lab | Jonathan Clayden | Clayden Group | 3-10 helix | peptide assembly | de novo | BBSRC | BrisSynBio | SynBio | Neil Paterson | minimal biology | Bristol BioDesign Institute | bioengineering |
