Hi guys, Welcome to the Advanced Video Search Engine, and you are watching Cytotoxic T cell function. That video is uploaded by Andrew Lilja at 2015-04-09T06:07:23-07:00. We are promoting this video only for entertainment and educational purpose only. So, I hope you like & enjoy it. [WdCiaIS2LV4]
| Name | Cytotoxic T cell function |
| Video Uploader | Video From Andrew Lilja |
| Upload Date | This Video Uploaded At 09-04-2015 13:07:23 |
| Video Discription | This animation was commissioned for the launch of the Centre for Advanced Molecular Imaging to highlight key themes of the research involved. In this scene, we follow a cytotoxic T cell (or killer T cell) as it patrols the body for potentially harmful pathogens. Using specialised T cell receptors (TCR) the immune cell probes antigens presented by the MHC-class I molecule on nearby cells and becomes activated when a foreign antigen is detected. A cascade of events follows, including production of inflammatory mediators and localised release of pore-forming proteins (perforin), compromising the target cell membrane and allowing the entry of destructive enzymes (granzymes), normally impermeant to the cell. Upon entry into the infected cell, granzymes induce cell death, thereby facilitating the clearance of the infection. WdCiaIS2LV4 |
| Category | Entertainment |
| Tags | Cytotoxic T Cell | Immunology (Field Of Study) | immunology | T cell | Major Histocompatibility Complex (Protein) | TCR | Perforin | Granzyme | Virus | Infection | Immune system |
