Hi guys, Welcome to the Advanced Video Search Engine, and you are watching CRISPR-Cas9 gene editing and how it works - with Jennifer Doudna. That video is uploaded by UC Berkeley at 2015-11-10T16:39:23-08:00. We are promoting this video only for entertainment and educational purpose only. So, I hope you like & enjoy it. [avM1Yg5oEu0]
| Name | CRISPR-Cas9 gene editing and how it works - with Jennifer Doudna |
| Video Uploader | Video From UC Berkeley |
| Upload Date | This Video Uploaded At 11-11-2015 00:39:23 |
| Video Discription | What is CRISPR-Cas9 and how does it work? How do we edit genes? Jennifer Doudna, biochemist at UC Berkeley, explains. The gene editing technique, created by UC Berkeley biochemist Jennifer Doudna and her colleague, Emmanuelle Charpentier, director of the Max Planck Institute of Infection Biology in Berlin, has taken the research and clinical communities by storm as an easy and cheap way to make precise changes in DNA in order to disable genes, correct genetic disorders or insert mutated genes into animals to create models of human disease. CRISPR-Cas9 is a hybrid of protein and RNA – the cousin to DNA – that functions as an efficient search-and-snip system in bacteria. It arose as a way to recognize and kill viruses, but Doudna and Charpentier realized that it could also work well in other cells, including humans, to facilitate genome editing. The Cas9 protein, obtained from the bacteria Streptococcus pyogenes, functions together with a “guide” RNA that targets a complementary 20-nucleotide stretch of DNA. Once the RNA identifies a sequence matching these nucleotides, Cas9 cuts the double-stranded DNA helix. Read more about CRISPR: http://news.berkeley.edu/2015/11/12/crispr-cas9-gene-editing-check-three-times-cut-once/ Video by Roxanne Makasdjian and Stephen McNally Cas9 Apo Structure image by Ben.lafrance CC BY-SA 4.0 https://commons.wikimedia.org/wiki/File:Cas9_Apo_Structure.png CRISPR animation provided by the Innovative Genomics Initiative http://www.berkeley.edu http://www.facebook.com/UCBerkeley http://twitter.com/UCBerkeley http://instagram.com/ucberkeleyofficial https://plus.google.com/+berkeley avM1Yg5oEu0 |
| Category | Education |
| Tags | UC Berkeley | Berkeley | University of California | UCB | higher education | CRISPR | Genetics (Field Of Study) | gene editing | DNA (Chemical Compound) | DNA Sequencing (Industry) | DNA Repair (Gene Group Membership Evidence) | Cas9 | Cas-9 | proteins | molecule | Biology (Media Genre) | Biologist (Profession) | Genome Editing | Jennifer Doudna | Doudna | CRISPR-CAS9 |
